TMG is a more active “methyl donor” than DMG with an additional methyl group in its chemical structure. It
is used to convert homocysteine to methionine, thus supporting cardiovascular and liver health.
TMG is found in a variety of plant and animal sources. Kirkman’s TMG derives from beets.
Methyl donors can help in the production of several brain chemicals. Some of the methionine from TMG is converted into SAMe (S-adenosylmethionine), which can help maintain healthy serotonin levels in the
body that may support mood, energy, concentration and a feeling of well-being.
Folic acid intake and levels in the body must be adequate for TMG to work biochemically. In some
individuals, the use of natural folinic acid may be more beneficial than folic acid, because folinic acid
already has attached four hydrogen atoms and one methyl group, thereby shortcutting the complicated
biochemical processes that assist purine and nucleotide synthesis. These processes are very important
in cell perception and response.